BioScaffolder 3D Bioprinter

The BioScaffolder is a modular, multi-headed 3D bioprinter equipped with multiple dispensing tools including unique core/shell tools for simultaneous dispensing of different materials.

Far from an ordinary bioprinter, the BioScaffolder has a unique temperature controlled piezoelectric micro-pipetting option for high performance printing at very low volumes (ideal for rare or expensive materials). It is highly versatile and adaptable for application specific configurations, making it the ideal advanced bioprinting platform.

Key Benefits:

  • Versatile, modular system
  • Low volume piezoelectric pipetting capabilities
  • Unique dispensing options
  • Easy scaffold design

As the exclusive distributor for the UK and Ireland, Analytik is proud to supply the 3D BioScaffolder from GeSiM. Through Analytik, you’ll have access to our team of experts to help develop your application and get the most out of your investment.

For more information, or to discuss your requirements with a product specialist, please call us on +44 (0)1954 232 776 or email info@analytik.co.uk.

Description

BioScaffolder Bioprinter

Tissue engineering and tissue regeneration have become a promising approach e.g. to cure severe bone injuries. Artificial tissue grown from differentiable cells often needs to be formed in a very particular 3-dimensional shape for implantation. Bio scaffolds can serve as a cell growth environment for such artificial tissues, further supporting supply of the cells and removal of the metabolites. More here.

The BioScaffolder Bioprinter is a modular instrument platform with up to four independent z-axes for running several dispensing tools. It can print a variety of pasty materials (hydrogels and biopolymers e.g. collagen, alginate, bone cement paste, polymer paste etc.) with up to three cartridges and has a unique optional heat controlled piezoelectric micro-pipetting system for pico-litre and nano-litre spotting of cells, proteins and curing/hardening substances on certain coordinates within a scaffold structure.

The BioScaffolder bioprinter has an unique piezoelectric pipetting option which allows non-contact dispensing of small volumes of drops (pico- and nano-litre) typically of cell suspensions or protein solutions on predefined coordinates of a bio-scaffold layer immediately after printing of this layer. The piezoelectric pipettor aspirates from standard 96/384 well plates. Liquid volumes of a few micro-litres work with this system. Also the flexibility of the separate piezoelectric pipettor allows the application of different cells at selected positions of the scaffolds, difficult to achieve by the cartridge dispenser. The dispensed spots usually have sizes between 50 and 200 microns. They can be placed on a scaffold layer immediately after printing and before the next scaffold layer goes on top e.g. particular proteins can be printed or even cell suspensions at very low viscosity.

The combination of both technologies is quite new and unique to the BioScaffolder printer and not available on any other competitive 3D printer.

Available modules:

  • Up to 4 individual lowering Z-axes for different tools
    • Combine different sized syringes and needles for high quality printing of different materials
  • Twin-tip piezo dispenser for mixing of droplets in flight, with control camera
    • Pico- and nano-litre dispensing capability
    • Print onto scaffold structures at well-defined locations
  • Melt electro-spinning printing option for printing of tiny thermoplastic structures
  • Unique core / shell tools:
    • Print composed strands of different materials – soft cell core material and hard shell material
    • Combine hard & soft materials in a co-axial manner
  • High-temperature, high-power piston extruder for high viscoelastic polymers
  • Peltier chiller for printing of hydrogels at low temperatures
  • Temperature controlled building platform

 

Interested in the 3D BioScaffolder? Request a quote or call us on +44(0)1954 232 776 to discuss your requirements.

Applications

  • Production of 3D scaffolds
  • Printing of live cells either embedded in scaffold material or seeding scaffolds by piezo spotting
  • Bio-ink & paste printing at high and low temperatures
  • Dispensing & curing of photosensitive materials

 

Video

An Introduction to the BioScaffolder 3D Bioprinter

 

Downloads

PDF Icon GeSiM BioScaffolder Info Sheet

PDF Icon GeSiM Bio-Scaffolder 3.2 Datasheet

PDF Icon GeSiM Bio-Scaffolder Technical Specifications

PDF Icon GeSiM Bio-Scaffolder FAQs

PDF Icon Bio-Scaffolder Tools at a Glance

 

Application Notes

PDF Icon Polycaprolactone Scaffolds – Pneumatic Printing

 

Papers

PDF Icon Three-Dimensional Printing of Hollow-Struts-Packed Bioceramic Scaffolds for Bone Regeneration

PDF Icon Evaluation of Cell Inkjet Printing Technique for Biofabrication

News & User Stories

PDF Icon Analytik reports on how the University of Brighton is using a BioScaffolder 3D Printer from GeSiM in its Centre for Regenerative Medicine

PDF Icon Queen’s University Belfast invests in state of the art 3D bioprinter

PDF Icon Reconstruction of a Human Scaphoid Bone

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