M815 Biopharma Microfluidizer® Processor

The M815 Microfluidizer® Processor high shear homogeniser takes the advantages of smaller Microfluidizer machines and applies them to a pilot scale/ production machine, with over 3 times the flow rate of the popular M-110-EH-30. Like all Microfluidizer® processors, the M815 utilises the fixed-geometry interaction chamber and constant pressure pumping system. This technology allows users to achieve smaller particle sizes — with more uniform distribution and scaleup guaranteed (both from lab scale and to larger scale units) — than can be obtained with other methods.

Key Features:

  • Flow rate of 1 – 1.2LPM, which is required for 100L clinical batches, and is ideal for 100L bio-reactors
  • Small batch capability; handles a minimum sample size of 200 ml
  • Compact design and mobility on casters
  • Monitors key process parameters with local display, with the option of CFR Part 11-compliant data acquisition and re-transmission
  • Facilitates safe and non-destructive processing of heat-sensitive materials
  • Cost-effective production
  • Assures batch-to-batch process repeatability

As the exclusive distributor for the UK and Ireland, Analytik is proud to provide the full Microfluidizer® range from Microfluidics. Through Analytik, you’ll have access to our team of experts to help develop your application and get the most out of your investment.

For more information, or to discuss your requirements with a product specialist, please call us on +44 (0)1954 232 776 or email info@analytik.co.uk.

Description

The M815 utilises Microfluidizer® proprietary high shear fluid processing technology for uniform droplet and particle size reduction, which enables the production of stable nanoemulsions, nanosuspensions, liposomes and the nanoencapsulation of actives. Additionally, Microfluidizer® technology offers the most efficient method for disruption of yeast, E. coli, plant and mammalian cells.

Like all Microfluidizer processors, the M815 utilises the fixed-geometry interaction chamber and constant pressure pumping system. This technology allows users to achieve smaller particle sizes – with more uniform distribution and scale-up guaranteed (both from lab scale and to larger scale units) – than can be obtained with other methods.

The M815 models are designed to bridge the gap between the biopharma lab scale (M-100EH) and production scale (M-700 Series) models, and they are ideal for manufacturing batches in the range of 100L-300L, which are necessary for PHII and PHIII clinical trials.

The M815 model was designed to bridge the gap between the lab scale (M-110EH) and production scale (M-700 series) models, and they are ideal for manufacturing batches in the range of 100L-300L.

 

Technical Specifications:

Description
M815
Pressure Range
up to 30,000 psi (2068 bar)
Flowrate range
1.0 – 1.2 L/min
Dimensions
W x D x H
57″L x 34″W x 72″H
(145 x 86 x 183 cm)
Weight
1,950 lbs (886 kg) with oil
1800 lbs (818kg) without oil

Interested in the M-815 Microfluidizer® Processor? Request a quote or call us on +44(0)1954 232 776 to discuss your requirements.

Applications

The M815 pilot production processor is recommended for processing:

  • Nanoemulsions (with and without API)
  • Nanodispersions
  • Microencapsulation
  • Deagglomeration
  • Cell Disruption

Downloads

PDF Icon M815 Microfluidizer® Processor High Shear Homogeniser Datasheet

PDF Icon Microfluidizer Processor Service & Support Brochure

Service & Support

Our Service Engineers are fully trained by the manufacturer and have in-depth technical experience spanning the full Microfluidics range, from benchtop and pilot-scale instruments through to full production-scale machines.

To increase longevity and reduce the risk of costly repairs, we provide preventative maintenance and user refresher training so you can have peace of mind that your equipment is being used correctly while being expertly maintained.

With an Analytik support plan you can rest assured that your Microfluidizer® is fully compliant with your internal and external standards. We also provide a range of support plans to suit all budgets and requirements. For more details please download our service and support brochure below:

PDF Icon Microfluidizer Processor Service & Support Brochure

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