M815 Biopharma

The M815 Biopharma high pressure homogeniser from Microfluidics, takes the advantages of Microfluidizer’s smaller machines and applies them to a pilot scale/ production machine with over 3 times the flow rate of the popular M-110-EH-30.

Like all Microfluidizer processors, the M815 utilises the fixed-geometry interaction chamber and constant pressure pumping system. This technology allows users to achieve smaller particle sizes – with more uniform distribution and scale-up guaranteed (both from lab scale and to larger scale units) – than can be obtained with other methods.

The M815 models are designed to bridge the gap between the biopharma lab scale (M-100EH) and production scale (M-700 Series) models, and they are ideal for manufacturing batches in the range of 100L-300L, which are necessary for PHII and PHIII clinical trials.

Key Benefits:

• Flow rate of 1 – 1.2LPM, which is required for 100L clinical batches, and is ideal for 100L bio-reactors.
• Small batch capability; handles a minimum sample size of 200 ml
• Compact design and mobility on casters.
• Monitors key process parameters with local display, with the option of CFR Part 11-compliant data acquisition and re-transmission.
• Facilitates safe and non-destructive processing of heat-sensitive materials.
• Cost-effective production
• Assures batch-to-batch process repeatability.