Description
Patented Optofluidic Force Induction (OF2i®)
Optofluidic Force Induction (OF2i®) is a non-destructive, parameter-free measuring method for particle counting, particle sizing and determination of particle concentration in liquid samples. Results are based on detection and counting of up to 1000 particles per minute in a continuous flow of sample through a measuring cell.
OF2i® measurement is:
- Continuous & with single-particle sensitivity to monitor dynamic processes as they occur in the sample, e.g. aggregates forming, reactions, dissolution, etc.
- Single-particle sensitivity is the basis for particle distributions which represent all the populations within polydisperse systems.
- With capacity to measure large volumes OF2i® detects ultra-low particle concentrations as well as large-particle tails, LPC, anomalies and outliers.
OF2i® particle sizing is available with lab devices BRAVE B-Curious and PAT device BRAVE B-Continuous. It forms the basis for analysis with BRAVE B-Aware, BRAVE B-Phat and BRAVE B-Elementary.
Unique combination OF2i®-Raman
The combined OF2i®-Raman setup uniquely uses single-particle tracking to capture the scattered Raman signals of individual particles at up to 30 frames per second. The recorded Raman spectra are then compared with a reference spectrum, while the OF2i® signal calculates particle size based on the speed of each particle.
OF2i®-Raman technology
The combination of OF2i® and Raman spectroscopy is unique and brings special benefits for your chemical analysis and particle characterisation.
- Easy particle detection and identification in flow
- High particle throughput of approx. 100 particles per minute
- Direct analysis in liquids with minimal preparation
- Wide range analysis (500 nm to 5 µm)
- Compact, benchtop device
- User-friendly and accessible to non-specialists
- Reproducible and reliable results
- Continuous analysis over extended periods
- Automated measurement and cleaning
- Optional ICP-ToF-MS connectivity
- High sensitivity for low particle concentrations
- Intuitive operation and data interpretation
- Real-time data livestream
OF2i®-Raman is available with BRAVE B-Elementary.
Additional large-particle detection for LPC and PFAT5 applications
BRAVE Analytics’ large-particle counting device, BRAVE B-Phat, detects large particles and aggregates from 2 µm to 80 µm in-flow and records their size based on dynamic imaging principles.
Large-particle detection is available with BRAVE B-Phat.
Interested in the Brave Analytics ®? Request a quote or call us on +44(0)1954 232 776 to discuss your requirements.